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Posted: Jun 7, 2024

Trending Topics in Health-System Pharmacy

Inpatient Insights

Despite FDA approval of seven next-generation antibiotics geared toward gram-negative infections between 2014 and 2019, clinicians still frequently treat resistant gram-negative infections with older, generic antibiotics that have suboptimal safety efficacy profiles.

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Posted: Jun 7, 2024

Calcium channel blocker and diuretic prescribing cascade may lead to adverse events

Drug Interactions

About a third of American adults in their 60s and 70s take five or more prescription drugs regularly. Often, some of these drugs are the result of prescribing cascades, which can be unnecessary and may cause avoidable adverse effects and adverse events.

Sonya Collins

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Posted: Jun 7, 2024

JACC review puts brakes on DOAC use

Anticoagulation

In January 2024, the Journal of the American College of Cardiology published a systematic review that included a detailed examination of randomized controlled trials exploring the efficacy and safety of direct oral anticoagulants (DOACs) and when they should not be considered standard treatment.

Corey Diamond, PharmD

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Posted: Jun 7, 2024

The jaw-dropping truth about medication-related osteonecrosis of the jaws

Osteonecrosis

For years, the American Association of Oral and Maxillofacial Surgeons (AAOMS) has been crafting strategies to tackle medication-related osteonecrosis of the jaws (MRONJ), formerly known as bisphosphonate-related osteonecrosis of the jaws. In an update published in the March 2024 issue of the Journal of Oral and Maxillofacial Surgery, experts from AAOMS explain revised diagnosis and management protocols, medication comparisons, and preventive measures aimed at empowering health care providers and enhancing patient care.

Aiya Almogaber, PharmD

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