A global increase in severe antimicrobial-resistant fungal infections of the skin—partly due to inappropriate use of topical antifungals and antifungal-corticosteroid combinations—has found its way to the United States.

FDA added a boxed warning to the osteoporosis drug denosumab (Prolia). The agency’s review of the drug indicated risks that warrant new prescribing information. For patients with chronic kidney disease (CKD)—especially those on dialysis or those with a concomitant diagnosis of mineral and bone disorder—FDA said they could develop severe hypocalcemia, or very low levels of calcium in the blood.

Early intervention with tecovirimat may stop an mpox infection from advancing to the stages of severe disease in people living with HIV (PWH), new research suggests.