A nasal spray version of naloxone (Rivive—Harm Reduction Therapeutics) is now on the FDA fast track for OTC clearance. According to the manufacturer, FDA is aiming for April 28, 2023, as an approval date after priority review. With cost and access in mind, Harm Reduction Therapeutics also noted that it would price the overdose antidote at about $18 per dose for sale to pharmacies, public-sector workers, and advocacy organizations. The nonprofit company will also donate one-tenth of its production, which is slated to reach 2 million doses annually.

The efficacy of statins for prevention of ischemic stroke due to blood clot is well established, but a new study in Neurology appears to possibly settle the debate over whether the drugs lower the odds of a first stroke due to intracerebral hemorrhage.

Researchers of a new study published in the New England Journal of Medicine compared outcomes in pregnant patients with opioid use disorder based on whether they received opioid agonist therapy with buprenorphine as opposed to methadone.