APhA Policy Manual

Harmonizing Kidney Function Assessment for Medication-Related Decisions

EDUCATION, CURRICULUM AND COMPETENCE FOR PHARMACY PHARMACY PRACTICE

APhA supports the systematic transition from Cockcroft-Gault estimated creatinine clearance to race-free estimated glomerular filtration rate adjusted for body surface area (eGFRBSAadj) as the preferred kidney function measure to inform medication-related decision making in adults.
APhA advocates for race-free eGFRBSAadj as the preferred standard for medication-related decision making for adults in PharmD curricula and licensing/board certification examinations.
APhA encourages expanded research evaluating race-free eGFRBSAadj use in medication-related decision making in adults using measured GFR, drug concentrations, or pharmacokinetic modeling as a comparator, especially for subgroups of adults usually underrepresented in clinical trials.